Product name:Pemetrexed disodium
CAS: 150399-23-8
Molecular Formula: C20H19N5Na2O6
Molecular Weight: 471.37
Product description:A structural core of pyrrole pyrimidine groups containing folic acid resistance agents, by destroying the normal metabolism of intracellular folic acid dependent process, inhibition of cell replication, thus inhibiting tumor growth. In vitro studies have shown that pemetrexed can inhibit thymidylic acid synthetase, dihydrofolate reductase and ammonia amide nucleotide formyl transferase activity, these enzymes are essential for synthetic folic acid enzyme, participate in the thymus pyrimidine nucleotide and Piao songs of biological and synthetic process of pemetrexed through transport carrier of folic acid and folic acid binding protein on the cell membrane transport system into the cell.