Simendan

Product name:Simendan
CAS: 131741-08-7
Molecular Formula: C14H12N6O
Molecular Weight: 280.28
Product description:This product is calcium sensitization agent, by changing the calcium combined with effective information transmission. This product directly combined with troponin, necessary to make the myocardial contraction induced by calcium ion to stability, space configuration of myocardial fibers of the protein to increase myocardial contraction force, and the heart rate, myocardial oxygen consumption has no obvious change. At the same time, this product has strong expansion blood vessel, through activation of adenosine triphosphate (ATP) sensitive potassium channels expand blood vessels, this article mainly expand peripheral vein, reduce cardiac preload, good for treatment of heart failure. When large doses when using this product, has certain phosphodiesterase inhibitory effect, can make the cAMP of myocardial cell concentration increased, give play to the role of additional positive strength.

 

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