Product name:Tenofovir disoproxil
CAS: 201341-05-1
Molecular Formula: C19H30N5O10P
Molecular Weight: 519.44
Product description:Tenofovir almost without gastrointestinal absorption, so the esterification, salt, become tenofovir ester fumaric acid salt. Tenofovir ester is water soluble, can be quickly absorbed and degraded into active substances tenofovir, then tenofovir into active metabolites for Norfolk WeiShuang phosphate. Within 1 ~ 2 h after drug tenofovir peak of blood. Tenofovir and food served as bioavailability can be increased by about 40%. For Norfolk WeiShuang phosphate intracellular half-life of about 10 h, 1 day delivery time. Due to the drug without metabolism of CYP450 enzyme system, therefore, caused by the enzyme and the possibility of other drug interactions between is very small. It mainly by glomerular filtration and drainage active tubular transport system.