Taurolidine (bis (1,1-dioxo-perhydro-1,2,4-thiadiazol-4) methane) is an active pharmaceutical ingredient (API) with antimicrobial and anti-lipopolysaccharide properties. Derived from taurine, is its immunomodulating effect reported to be mediated by a primer, and the activation of macrophages and polymorphonuclear leukocytes.Taurolidine also shows some antitumor properties with the positive results obtained in early clinical trials manufacture of a medicament for the treatment of gastrointestinal cancers and tumors of the central nervous system. It is a lifesaving antimicrobial severe abdominal sepsis and peritonitis. In severe infections and surgical taurolidine in Surgical Oncology active against a broad spectrum of microorganisms, including gram-positive bacteria, gram-negative bacteria, fungi, mycobateria also bacteria that are resistant to various antibiotics, such as MRSA, VISA VRSA ORSA VRE.
