Posted in Pharmaceutical Raw Materials 16. Dec, 2011 · Edit
Benzimidazole is a heterocyclic aromatic polycyclic compounds formed by the benzene and imidazole blend, molecular formula C7H6N2. Vitamin B12 molecule, 5,6 – dimethyl-benzimidazole cobalt center is connected with the base. Benzimidazole and imidazole is similar to preparation of heterocyclic carbene is commonly used raw materials. Such carbene by the N, N’-disubstituted benzimidazole alkali in 2 – bit deprotonated obtained for the preparation of transition metal carbene complexes.Copper has excellent thermal conductivity and electrical conductivity, widely used in industrial production in the thermal cycling system. But with the heat transfer devices made of copper after a certain time, the copper deposited on the surface reduces the heat transfer efficiency of the dirt, so the need for regular cleaning with hydrochloric acid. As the acidic solution has some corrosion on copper, generally require cleaning by adding corrosion inhibitors. Most acid corrosion inhibitors for the nitrogen, sulfur or oxygen compounds, such as benzotriazole, imidazoline, imidazole derivatives.
Derivatives of two nitrogen hetero-atom-containing five-membered ring compounds, which can be formed on the surface corrosion layer of copper to reduce corrosion, but also environmentally friendly and low toxicity, etc., has a corrosion inhibitor in the pickling special significance. S. Raicheva, who studied the imidazole derivatives as corrosion inhibitors of stainless steel pickling, indicating that the inhibition effect than alkyl imidazole alkyl imidazole; R. Gasparac, to address several imidazole derivatives in the 015 mol / L hydrochloric acid inhibition mechanism in solution; Zhang and other studies of benzimidazole derivatives as corrosion of stainless steel and carbon steel pickling.Benznidazole (INN, at one time commercialised along Hoffman-La Roche below the brands Rochagan and Radanil) is an antiparasitic medicinal drug expended inward the discussion from Chagas disease. It has chemical mechanism of action mechanism constitutes ambitious to breakthrough merely them follows up on microtubules. Roche given the applied science and compensates to bring about benznidazole to the Brazilian governance.
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