micafungin clean by Coleophoma empetri of modification of natural products, chemical synthesis of new spines white fungus element class of antifungal drugs; It to smooth candida c. albicans, candida, heat generation of candida, g soft candida and nearly smooth candida have good inhibitory activity, also have good in vitro inhibitory activity to aspergillus, but for new cryptococcus, sickle bacteria, joint bacteria and Bai Jili wool spore bacteria such as no inhibitory activity. Micah Finn net (Micafungin) developed by Japanese fujisawa company, listed in Japan in December 2002, commodity name Fungusrd, in March 2005 passed the FDA certification, is currently only being approved for the treatment of esophageal candida infection, bone marrow transplant and ADS the prevention and treatment of patients with neutropenia.
micafungin net for spine white fungus element class broad-spectrum antifungal drugs, for candida, music bacterium have broad antifungal effect, resistance to fluconazole and dependent triaconazole candida also have effect. And then to decide by inhibiting the fungal cell wall - D - glucan synthesis play a role of antifungal. The clinical isolation of candida and aspergillus strong exterminate action, but for cryptococcus neoformans is invalid. This product by aspergillus species of this genus and antibacterial spectrum is wide, all kinds of fungi sensitivity order of this product: white candida > smooth candida tropical candida > > Portugal a silk silk, candida yeast > crewe > nearly smooth candida. This product with amphotericin B, can significantly increase the drug to the yeast cryptococcus ball antibacterial activity, also can make the antibacterial spectrum broadening of amphotericin B.
