Cilostamide

Cilostamide

Product name : Cilostamide

CAS No. : 68550-75-4

Molecular Formula :  C20H26N2O3 

Molecular Weight :  342.43

Product description :
It is white solid.Cilostamide (OPC 3689) is a specific phosphodiesterase 3 (PDE3) inhibitor. The compound has been shown to block DNA binding of p-Stat3, increase cAMP levels and block the effects of insulin and IGF-1 on meiosis. Additionally, Cilostamide activates K(ATP) channels and produces hyperpolarization in rat mesenteric artery studies. In F/B cells Cliostamide has been reported to inhibit the IGF-1 induced phosphorylation of the apoptotic protein, Bad.

 

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