Product name : Sulfamethoxazole
Synonyms : 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide;Sulfisomezole;Sulfamethoxizole;Sinomin;
CAS No. : 723-46-6
Molecular Formula : C10H11N3O3S
Molecular Weight : 253.279 g/mol
Product description :
Sulfamethoxazole (abbreviated SMZ or SMX) is a sulfonamide bacteriostatic antibiotic.
It is most often used as part of a synergistic combination with trimethoprim in a 5:1 ratio in co-trimoxazole (abbreviated SMZ-TMP and SMX-TMP,or TMP-SMZ and TMP-SMX), also known under trade names such as Bactrim, Septrin, or Septra; in Eastern Europe it is marketed as Biseptol. Its primary activity is against susceptible forms of Streptococcus, Staphylococcus aureus (including MRSA), Escherichia coli, Haemophilus influenzae, and oral anaerobes. It is commonly used to treat urinary tract infections. In addition it can be used as an alternative to amoxicillin-based antibiotics to treat sinusitis. It can also be used to treat toxoplasmosis and it is the drug of choice for Pneumocystis pneumonia, which primarily affects patients with HIV.