Product name: Diammonium Glycyrrhizinate and Sodium Chloride Injection
Product description:The main ingredients of this product is glycyrrhizic acid.The accessories are sodium chloride, water for injection.It is colorless clear liquid.
Chemical name: 20β-carboxy -11-- oxo oleanane is -12---en-3β-based-2-O-β-D-glucopyranoside acid base-α-D-glucopyranoside acid two ammonium salt.
Molecular formula: C42H68N2O16
Molecular Weight: 857.01
Application:For associated with elevated alanine aminotransferase in chronic persistent hepatitis and chronic active hepatitis.
Specifications:250ml,glycyrrhizic acid and 0.15g sodium chloride 2.25g.
Dosage:Intravenous infusion, once a bottle (250ml), 1st.
Adverse reactions:
① shock: occasional shock, should give full attention when an exception occurs, immediately stop, make the appropriate treatment;
② pseudo-aldosterone: As the incremental or long-term use, there may be a high degree of hypokalemia, increased incidence of hypokalemia, increased blood pressure, sodium, fluid retention, edema, weight gain and other pseudo-aldosterone risk Therefore, to fully observe the determination of serum potassium values, etc., found in unusual circumstances, should stop the administration. In addition, as a result of hypokalemia may be off a sense of power, low muscle strength and other symptoms.
Other adverse reactions: a small number of patients may have high blood pressure, dizziness, headache, nausea, abdominal discomfort, bloating, rash and fever.
Taboo:Allergic to the chemicals were banned; severe hypokalemia, hypernatremia, hypertension, heart failure, kidney failure patients hanged.
Notes:
1.During the course of treatment, such as conditions permit, should be regularly measured blood pressure and serum potassium and sodium concentrations.
2 product can cause the apparent increase in aldosterone, in the course of treatment, such as fever, rash, hypertension, sodium retention, low potassium blood, etc., should be discontinued.
3.limit to Pregnant and lactating women .
Pediatric Use:Newborns, infants and young children's dosage and adverse reactions has not been determined, is not recommended to the FDA.
Geriatric medicine;Based on clinical experience, elderly side effects such as hypokalemia higher incidence, should observe the patient's condition, use caution.
Drug Interactions :And ethacrynic acid, furosemide, thiazide B, triclosan and a thiazide diuretic such as use, its diuretic effect could enhance the product contained in the row of glycyrrhizic acid potassium, easily lead to a decline in serum potassium values ??should be special attention to the determination of serum potassium values ??and so on.
Overdosage:Be incremental, the maximum daily dosage of 2 bottles (500ml).
Pharmacological effects:This product has a strong anti-inflammatory, protect the liver cell membrane and improve liver function. Pharmacological experiments show that mice by oral administration of the product can reduce carbon tetrachloride, thioacetamide and D-galactosamine-induced serum alanine aminotransferase, aspartate aminotransferase enzymes. This product can significantly reduce the D-galactosamine form of liver damage and improve the immune factors on the form of chronic liver damage.
Storage:Sealed.
Packing:Infusion bottles. 250ml / bottle.
Valid time:24 months.