Sparsomycin is a compound, initially apparent as a metabolite of the bacillus Streptomyces sparsogenes, which binds to the 50S ribosomal subunit and inhibits protein synthesis. It is a nucleotide analogue.By administering the radioactively labeled L-methionine to S. sparsogenes, they ample out that it was the a lot of apparent forerunner for C-4' and C-5' atoms of the sparsomycin.This award led them to an acceptance that an agitator alleged serine transhydroxymethylase could be amenable for the ascertainment by about-face of the cysteine to serine residue.
